Nuclear Medical Application F18 Hot Cells

Fluorine-18 (F18), a widely used radioactive isotope in nuclear medicine, plays a pivotal role in positron emission tomography (PET) imaging, particularly in the form of 18F - fluorodeoxyglucose (FDG). Given F18's short half-life of approximately 109.8 minutes and its high - energy positron emissions, specialized handling is crucial. Our F18 - Specific Nuclear Medicine Hot Cell is meticulously engineered to meet these exacting requirements, ensuring safe and efficient processing of F18 - based radiopharmaceuticals.

F18 emits high - energy positrons, which upon annihilation with electrons produce gamma rays of 511 keV. To safeguard operators and the surrounding environment, our hot cell is constructed with multi - layer shielding. The primary layer consists of lead - lined stainless steel, with a lead thickness of [X] mm, providing substantial attenuation of gamma radiation. Additionally, a secondary layer of high - density polyethylene is incorporated to moderate the high - energy positrons, reducing bremsstrahlung radiation. This dual - layer design effectively minimizes external radiation levels to well - below regulatory limits, even during high - activity F18 processing.

Maintaining a sterile and particle - free environment is non - negotiable in F18 radiopharmaceutical production. Our hot cell achieves ISO 14644 - 1 Class A (equivalent to US Fed - Std 209E Class 1) cleanliness standards. A vertical laminar down - flow airflow system, powered by ultra - low penetration air (ULPA) filters with 99.999% efficiency for particles as small as 0.12 μm, continuously purifies the air within the hot cell. The laminar flow pattern ensures that any potential contaminants are quickly removed, preventing cross - contamination during sensitive F18 labeling and formulation processes.

We understand the importance of operator well - being during extended F18 handling sessions. The hot cell's interior layout is ergonomically optimized. The work surface is adjustable, accommodating operators of different statures, and is positioned at an ideal height to reduce fatigue. The viewing window, made of thick lead - glass with anti - glare properties, offers an unobstructed view of the work area, while maintaining robust radiation shielding. Manipulator arms or glove ports are designed for maximum dexterity, allowing operators to perform intricate tasks such as pipetting F18 - containing solutions with precision.

Recognizing that every nuclear medicine facility has unique requirements, we offer a range of customizable options for our F18 Hot Cell. Whether you need additional workstations for parallel processing, integration of specialized equipment such as automated F18 labeling systems, or enhanced shielding for higher - activity applications, our team of experts can tailor the hot cell to your exact specifications. We also provide options for modular expansion, allowing you to adapt the hot cell as your facility's needs grow.

• FDG Synthesis: Efficient production of 18F - FDG, the most commonly used radiotracer in PET imaging, for cancer diagnosis, staging, and treatment monitoring.
• Research Applications: Handling of F18 for the development of new radiopharmaceuticals and the investigation of novel imaging agents in pre - clinical and clinical research.
• Patient - Specific Dosage Preparation: Precise formulation of F18 - based radiopharmaceuticals to meet the individualized needs of patients undergoing PET imaging.

Our F18 - Specific Nuclear Medicine Hot Cell is designed, manufactured, and tested in strict accordance with international regulatory standards, including those set by the International Atomic Energy Agency (IAEA), the US Food and Drug Administration (FDA), and the European Union's Medical Device Regulation (MDR). Each hot cell undergoes rigorous quality control checks, including radiation shielding verification, air - flow performance testing, and aseptic environment validation, to ensure its reliability, safety, and compliance.

• Isotope - Specific Expertise: Our hot cell is designed specifically for F18 handling, taking into account its unique radioactive properties and the requirements of radiopharmaceutical production.
• Proven Track Record: With years of experience in the nuclear medicine industry, our hot cells are trusted by leading medical facilities and research institutions worldwide.
• Comprehensive Support: We offer end - to - end support, including installation, operator training, maintenance, and technical assistance, to ensure the seamless operation of your hot cell.

Contact us today to learn more about how our F18-Specific Nuclear Medicine Hot Cell can enhance your nuclear medicine capabilities and take your radiopharmaceutical production to the next level.